NOT KNOWN FACTS ABOUT FENTANYL MEDICAL USAGE

ritlecitinib will enhance the level or effect of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Carefully. Ritlecitinib inhibits CYP3A4 substrates; coadministration boosts AUC and peak plasma concentration sensitive substrates, which can improve risk of adverse reactions.Prolonged use during pregnancy can